Antonina Mitrofanova lab
Computational Systems Oncology
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After completing my PhD in Computer Science at NYU with Bud Mishra, I obtained my PostDoctoral training in Computational Systems Biology at Columbia University Cancer Center under the mentorship of Andrea Califano (NSF Computing Innovation Fellowship) and Michael Shen (PCF Young Investigator Award).
At Rutgers, my laboratory develops computational algorithms to elucidate genomic and epigenomic
mechanisms of therapeutic resistance in oncology and to identify optimal
treatment strategies for cancer patients. Our goal is to build a marker panel to predict patients at risk of resistance and patients with favorable treatment response, with further
advise on their optimal therapeutic course.
August 2018 Our collaborative paper with Chris Hourigan's lab (NHLBI/NIH) "Targeted RNA-Sequencing For The Quantification Of Measurable Residual Disease In Acute Myeloid Leukemia" has been accepted to Haematologica. Congratulations, Sheida!
July 2018 My PhD student Nusrat Epsi was selected to receive Katrina Kehlet Graduate Award from NJ HIMSS. Congratulations, Nusrat!
May 2018 My PhD student Sukanya Panja received the Gallo Award for Scientific Excellence in Cancer Research at The 2018 Annual Retreat on Cancer Research in New Jersey. Congratulations, Sukanya!
April 2018 Our paper "Integrative (epi) genomic analysis to predict response to androgen-deprivation therapy in prostate cancer" has been accepted to EBioMedicine. Congratulations, Sukanya!
April 2018 Our lab received a Summer Student Intern Project grant, awarded by Rutgers SHP. Thank you, SHP!!
April 2018 I have been honored to receive an Excellence in Research Award from Rutgers SHP, sponsored by New Jersey Health Foundation. Thank you very much for this honor!!
Jan 2018 Our collaborative paper with Michael Shen's lab (Columbia University) "Differential requirements of androgen receptor in luminal progenitors during prostate regeneration and tumor initiation" has been accepted to eLIFE. Congratulations, Nusrat!
August 2017 My PhD student, Sheida Hayati, has received a travel grant for the Cold Spring Harbor meeting "Forty Years of mRNA Splicing". Conratulations, Sheida!
May 2017 My PhD student, Nusrat Epsi, has been awarded a Grace Hopper Celebration (GHC) Student Scholarship grant to attend a GHC of Women in Computing conference. Congratulations, Nusrat!
May 2017 Our lab received a Summer Student Intern Program grant, sponsored by the New Jersey Health Foundation and awarded by Rutgers SHP. My PhD student Nusrat Epsi was selected to execute this project. Congratulations, Nusrat!
May 2017 Editorial about our Cancer Discovery paper in Nature Review Urology. Article.
May 2017 Our Cancer Discovery paper is highlighted by the ScienceDaily! Link.
April 2017 Editorial about our paper in European Urology. Article.
April 22, 2017 We joined the March for Science in NYC! Facebook.
April 2017 Our European Urology paper is highlighted by the Prostate Cancer Foundation! Twitter.
April 2017 Our collaborative paper with Cory Abate-Shen's lab (Columbia University) "Transdifferentiation as a mechanism of treatment resistance in a mouse model of castration-resistant prostate cancer" has been accepted to Cancer Discovery. Congratulations, Sheida!
April 2017 My PhD student, Laura Harris, has been awarded a Center for Teaching Excellence faculty grant from Davenport to publish two of her PhD papers. Congratulations, Laura!
April 2017 We are in the news celebrating Sheida's achievements! Press release.
March 2017 Our collaborative paper with Cory Abate-Shen's lab (Columbia University) "Co-clinical analysis of a genetically-engineered mouse model and human prostate cancer reveals significance of NKX3.1 expression for response to 5a-reductase inhibition" has been accepted to European Urology. Congratulations, Sukanya!
March 2017 My PhD student, Sheida Hayati, has been awarded a New Jersey Commission on Cancer Research (NJCCR) Pre-Doctoral Fellowship from New Jersey Department of Health. Congratulations, Sheida!
January 2017 Our collaborative paper with Michael Shen's lab (Columbia University) "A computational systems approach identifies synergistic specification genes that facilitate lineage conversion to prostate tissue" has been accepted to Nature Communications.
January 2017 My PhD student, Sheida Hayati, has been selected for an NIH Summer Internship in Biomedical Research. She will spend this summer in Chris Hourigan's lab at NIH.
June 2016 Our collaborative paper with Cory Abate-Shen's lab (Columbia University) "Identification of an NKX3.1-G9a-UTY transcriptional regulatory network that controls prostate differentiation" has been published in Science , paper.
April 2016 Our lab has been awarded a Dean's Intramural Pilot grant from the Rutgers School of Health Professions!